Reference catalog · 20 compounds · 5 mechanism classes
Fat Loss & Metabolic Research Compounds
A reference catalog of metabolic research compounds, organized by mechanism of action: mitochondrial uncouplers, AMPK activators, β-oxidation modulators, amylin analogues, and myostatin / growth-axis inhibitors. Each compound is presented for educational reading of the published research literature — not as medical advice and not as a recommendation for personal use. Consult a licensed clinician before considering any compound described here, particularly the investigational drugs that have not received regulatory approval for the indications discussed.
Mechanism Comparison
| Class | Pathway | Key Examples | Half-Life | Products |
|---|---|---|---|---|
UCPMitochondrial Uncoupler | Dissipates proton gradient → heat, raising basal metabolic rate | BAM-15, 2,4-DNP analogs | 4–8 hours | 2 |
AMPKAMPK Activator | Mimics cellular low-energy state → fatty acid oxidation | 5-Amino-1MQ (NNMT inhibitor) | 12–16 hours | 3 |
LIPLipolysis / β-Oxidation | HSL activation, fat mobilization without affecting IGF-1 | AOD-9604, Adipotide | 30 min – 2 hours | 5 |
AMYAmylin / Satiety | Amylin-receptor signaling; gastric-emptying and satiety pathways in preclinical models | Cagrilintide, Amycretin | 7+ days (long-acting) | 0 |
MYOMyostatin / Growth-Axis | Myostatin-pathway inhibition; studied for lean-mass preservation in preclinical models | ACE-031, Follistatin-344 | varies | 0 |
Mitochondrial Uncoupler
Dissipates proton gradient → heat, raising basal metabolic rate
Half-life 4–8 hours
AMPK Activator
Mimics cellular low-energy state → fatty acid oxidation
Half-life 12–16 hours
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Lipolysis / β-Oxidation
HSL activation, fat mobilization without affecting IGF-1
Half-life 30 min – 2 hours
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Other Metabolic Compounds
Metabolic modulators outside the main mechanism classes.
L-Carnitine 400mg/mL
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