The Complete Clav Protocol: Research Reference
This is the full reference document for the Clavicular protocol — all compounds, all layers, all dosing data drawn from published research.
Protocol Overview
The Clav protocol is a five-layer research stack built for simultaneous fat loss, GI protection, skin optimization, and lean mass preservation.
| Layer | Compound | Mechanism | Role |
| 1 | Retatrutide (GLP-3 R) | Triple GLP-1/GIP/GcgR agonist | Fat loss core | ||||
| 2 | BPC-157 | NO system + EGF upregulation | Gut protection | ||||
| 3 | GHK-CU | Collagen + VEGF + Cu-SOD | Skin GLOW | ||||
| 4 | SNAP-8 | NMJ ACh inhibition | Expression wrinkle KLOW | ||||
| 5 | CJC-1295/Ipamorelin | GHRH + GHRP dual secretagogue | Lean mass | Layer 1: Retatrutide Escalation ProtocolFrom Phase 2 trial (published NEJM): | Phase | Dose | Weeks |
| Initiation | 2mg/week | 1-4 |
| Escalation 1 | 4mg/week | 5-8 |
| Escalation 2 | 8mg/week | 9+ |
Phase 2 result at 8mg/week, 48 weeks: −28.7% body weight. Trajectory not plateaued at trial end.
Reconstitution: 5mL BAC water into 15mg vial → 3mg/mL
Layer 2: BPC-157 Protocol
Begins week 1, concurrent with Retatrutide initiation.
- Reconstitution: 10mL BAC water into 10mg vial → 1mg/mL
- Research frequency: Once to twice daily in most preclinical studies
- Route: Subcutaneous in most published research
Layer 3: GHK-CU Protocol
- Reconstitution: 10mL BAC water into 50mg vial → 5mg/mL
- Research dose: 1-2mg in most preclinical models
- Protect from light after reconstitution
- Can begin anytime during protocol
Layer 4: SNAP-8 Protocol
- Reconstitution: 5mL BAC water → 1mg/mL
- Typically administered in research alongside GHK-CU
- Often studied as topical preparation as well (0.1-2% in carrier)
Layer 5: CJC-1295/Ipamorelin
- Reconstitution: 5mL BAC water → 1mg/mL
- Add during periods of active training load
- Timing: Pre-sleep in most GH secretagogue research (GH pulse amplitude largest during sleep)
Total Protocol Cost
| Compound | Vial | Price |
| GLP-3 R 15mg | 1 | $189.99 |
| BPC-157 10mg | 1 | $59.99 |
| GHK-CU 50mg | 1 | $50.00 |
| SNAP-8 | 1 | $45.00 |
| CJC-1295/Ipamorelin | 1 | $50.00 |
| BAC Water 10ml | 2 | $19.98 |
| Total | $414.96 |
All information is for laboratory research reference only. Not medical advice.
